aminotransferase
UK[əˌmiːnəʊˈtrænsfəreɪz]US[əˌmiːnoʊˈtrænsfəreɪs]
n
An enzyme that catalyzes the transfer of an amino group from one molecule to another.
Morpheme Breakdown
amino
transfer
ase
amino
transfer
ase
Etymology
The word 'aminotransferase' is a modern scientific compound built from established morphemes. The component 'amino' traces its lineage to ancient salts associated with the Egyptian god Ammon, evolving into a term for nitrogen-based compounds. 'Transfer' is a direct borrowing from Latin, literally meaning 'to carry across,' perfectly describing the enzyme's function. The suffix '-ase,' derived from Greek via early enzyme names, systematically marks it as a protein catalyst. Thus, the word's construction transparently and logically describes an enzyme that carries an amino group across from one molecule to another.
Analysis
Structure: amino + transfer + ase
- amino: From the chemical term 'amine', itself from 'ammonia', ultimately from Latin sal ammoniacus (salt of Ammon). In biochemistry, it denotes the presence of an NH₂ group. Functional role: Specifies the chemical group involved.
- transfer: From Latin transferre (trans- 'across' + ferre 'to carry'). Functional role: Denotes the core action of moving something from one place to another.
- ase: A suffix used in biochemistry to denote an enzyme, from 'diastase', ultimately from Greek διάστασις (diastasis) 'separation'. Functional role: Noun suffix indicating an enzyme.
Examples
Alanine aminotransferase is a key enzyme measured in liver function tests.
The reaction catalyzed by an aminotransferase is often reversible.
Aspartate aminotransferase plays a crucial role in amino acid metabolism.