calcium-channel
UK[ˈkalsɪəm ˌtʃan(ə)l]US[ˈkælsiəm ˌtʃæn(ə)l]
n
A protein pore in a cell membrane, especially of a muscle or nerve cell, that allows calcium ions to pass through and is involved in various physiological processes.
Morpheme Breakdown
calcium
channel
calcium
channel
Etymology
The term is a modern scientific compound, combining the name of a chemical element with a word for a passageway. 'Calcium' originates from the Latin calx, meaning limestone, as the metal was first isolated from lime. 'Channel' traces back to the Latin canalis, referring to a pipe or watercourse. In the 20th century, with advances in cell biology and electrophysiology, these roots were fused to create a precise term for the transmembrane protein structures that selectively permit calcium ions to flow into cells, crucial for functions like muscle contraction and neuronal signaling. The compound thus logically describes a dedicated conduit for calcium ions.
Analysis
Structure: calcium + channel
- calcium: From Latin calx (limestone, lime). The element name derived from the Latin word for lime.
- channel: From Old French chanel, from Latin canalis (pipe, groove, channel). The morpheme denotes a passage or conduit.
Examples
The drug works by blocking specific calcium-channels in the heart muscle.
Malfunction of neuronal calcium-channels is implicated in some neurological disorders.
Researchers are studying the structure of the calcium-channel to develop new therapeutics.