首页

monoclonal

UK[ˌmɒn.əˈkləʊ.nəl]US[ˌmɑː.nəˈkloʊ.nəl]
adj

relating to or being a clone derived from a single individual, cell, or gene.

adj

(of an antibody) produced by a single clone of cells, and therefore consisting of identical antibody molecules.

Morpheme Breakdown

mono
clon
al
mono

single

clon

clone

al

adjective suffix

Etymology

the term 'monoclonal' is a modern scientific coinage, constructed from classical elements to describe a precise biological concept. the prefix 'mono-', from greek 'monos' (single), establishes the idea of singularity. this is combined with 'clon', a truncation of 'clone', which itself originates from the greek 'klōn', meaning a twig or slip suitable for propagation, metaphorically extended to mean genetically identical copies. the latin-derived adjectival suffix '-al' is then appended to form the complete word. thus, the literal construction 'pertaining to a single clone' elegantly conveys the modern meaning of something derived from or consisting of genetically identical cells, such as monoclonal antibodies used in medicine.

Analysis

Structure: mono (single) + clon (clone) + al (adjective suffix) mono: from greek 'monos', meaning 'alone, single, only'. serves as a prefix indicating singularity. clon: a direct substring of 'clone', from greek 'klōn', meaning 'twig, slip'. serves as the root, referring to a group of identical cells or organisms. al: from latin '-alis', an adjective-forming suffix meaning 'pertaining to'.

Examples

monoclonal antibodies are used in targeted cancer therapies.

the research focused on producing a monoclonal cell line.

the test detects the disease using a monoclonal reagent.

monoclonal – Meaning, Etymology & Word Origin | OpenEtymology