serotonergic
UK[ˌsɛrətəʊˈnɜːdʒɪk]US[ˌsɛrətoʊˈnɜːrdʒɪk]
adj
Relating to, releasing, or involving serotonin in the transmission of nerve impulses.
Morpheme Breakdown
serotonin
erg
ic
serotonin
erg
work
ic
of, pertaining to, or characterized by
Etymology
The word is a modern scientific compound built from the name of the neurotransmitter 'serotonin' and the Greek-derived combining form '-ergic'. 'Serotonin' itself is a mid-20th century coinage, blending the Latin serum (referring to blood serum, where it was first isolated) and the Greek tonos ("tension, tone"), hinting at its vasoconstrictive effect. The element '-ergic' derives from Greek ergon ("work"), used in biological terms to denote an agent that activates or works upon a specific system. Thus, 'serotonergic' logically describes neurons or drugs that work by means of or have an effect on the serotonin system, tracing a direct path from the ancient concepts of "serum," "tone," and "work" to a precise neurochemical function.
Analysis
Structure: serotonin + erg + ic
serotonin: A coined term (from Latin serum and Greek tonos), functioning as the specific chemical compound name.
erg: From Greek ergon, meaning "work" or "activity". In this word, it functions as a combining form meaning "acting" or "having an effect on".
ic: From Latin -icus, Greek -ikos, a suffix forming adjectives meaning "of, pertaining to, or characterized by".
Examples
Serotonergic neurons are primarily located in the raphe nuclei of the brainstem.
Many antidepressants function by enhancing serotonergic activity.
The drug has a potent serotonergic effect, which explains its side effect profile.