single-stranded
UK[ˈsɪŋɡlˌstrændɪd]US[ˈsɪŋɡlˌstrændɪd]
adj
(of a nucleic acid molecule) consisting of a single linear chain of nucleotides, rather than the paired double helix structure.
Morpheme Breakdown
single
strand
ed
single
one
strand
thread
ed
adjective suffix
Etymology
The term is a modern scientific compound, built from common English elements to describe a specific molecular structure. The first element, 'single', traces back to Latin singulus, emphasizing singularity. The second, 'strand', evolved from an Old English word for a shore or edge to metaphorically denote a single filament or thread, apt for describing a linear polymer. The suffix '-ed' converts the noun phrase into an adjective, indicating the possession of the quality of being a single thread. Thus, the literal construction "having a single thread" perfectly captures the molecular biology concept of a nucleic acid chain that is not paired with a complementary strand.
Analysis
Structure: single (one) + strand (thread) + ed (adjective suffix)
- single: From Latin singulus (one, individual). Functional role: Modifying root, indicating the number one.
- strand: From Old English strand (shore, edge) and Proto-Germanic, later developing the sense of a single thread or filament. Functional role: Core root, denoting a thread-like structure.
- ed: From Old English -ede, -od, an adjectival suffix used to form past participles and adjectives meaning "having the quality of". Functional role: Derivational suffix, forming an adjective from a noun phrase.
Examples
The viral genome is composed of single-stranded RNA.
Researchers developed a probe to detect single-stranded DNA breaks.
The stability of a single-stranded molecule is lower than that of its double-stranded counterpart.