exon
UK[ˈɛksɒn]US[ˈɛksɑːn]
n
A segment of a DNA or RNA molecule containing information coding for a protein or peptide sequence, which is expressed in the final mature RNA molecule after splicing.
Morpheme Breakdown
ex
on
ex
out
on
unit/particle
Etymology
The term "exon" is a modern scientific coinage, created in the late 1970s by American molecular biologist Walter Gilbert. It is a portmanteau constructed from the phrase "expressed region" and the Greek-derived suffix "-on." The prefix "ex-" (from Latin) was chosen for its sense of "out" or "expressed," directly contrasting with "intron" (from "intragenic region"), where "in-" means "within." The "-on" suffix follows a well-established pattern in biochemistry and physics for naming fundamental subunits. Thus, the word's logic perfectly captures its function: it is the expressed unit of a gene that exits the nucleus to guide protein synthesis.
Analysis
Structure: ex (out) + on (unit/particle)
- ex: A Latin prefix meaning "out of, from, beyond." In this context, it indicates being expressed or exiting the intron sequence.
- on: A suffix of Greek origin (from -ον, a neuter noun ending) used in modern scientific terminology to form nouns denoting basic units or particles (e.g., proton, codon, photon).
Examples
The exons of a gene are spliced together to form the final messenger RNA.
Mutations within an exon are more likely to alter the protein's structure.
The research focused on identifying all the exons in the genomic sequence.