leukotriene
UK[ˌluː.kəʊˈtraɪ.iːn]US[ˌluː.koʊˈtraɪ.iːn]
n
Any of a group of biologically active compounds derived from arachidonic acid, involved in inflammatory and allergic reactions.
Morpheme Breakdown
leuko
triene
leuko
white
triene
chemical suffix
Etymology
The term 'leukotriene' is a modern scientific coinage from the late 20th century, directly constructed from greek and chemical vocabulary. The first element, leuko-, references leukocytes (white blood cells), as these compounds were first discovered in and isolated from these cells. The second element, -triene, is derived from organic chemistry, denoting the presence of three conjugated carbon-carbon double bonds, a defining structural feature of the first identified leukotrienes. Thus, the word's literal meaning, "white cell triene," precisely reflects its biological origin and chemical structure, linking the cellular source to the specific molecular architecture responsible for its potent role in mediating inflammation.
Analysis
Structure: leuko (white) + triene (chemical suffix)
- leuko: from greek leukos (white, bright, clear). functional role: a combining form denoting whiteness or relating to leukocytes (white blood cells).
- triene: from the chemical term triene, indicating a compound containing three double bonds in its molecular structure. functional role: a suffix specifying the chemical nature of the compound.
Examples
Leukotrienes are key mediators in the pathophysiology of asthma.
The drug works by inhibiting the synthesis of inflammatory leukotrienes.
Research is focused on developing new antagonists for leukotriene receptors.