immunohistochemical
UK[ˌɪmjʊnəʊˌhɪstəˈkɛmɪkəl]US[ˌɪmjənoʊˌhɪstoʊˈkɛmɪkəl]
adj
Relating to or denoting the application of immunological techniques to histochemistry, especially for identifying specific cellular components using antibodies.
Morpheme Breakdown
immuno
histo
chemical
immuno
immune
histo
tissue
chemical
chemical
Etymology
The word 'immunohistochemical' is a modern scientific compound, constructed in the mid-20th century from three classical elements. The first part, 'immuno-', derives from the Latin concept of exemption, which evolved to signify the body's system of defense. The second, 'histo-', originates from the Greek word for a woven web, later specialized to mean biological tissue. The final component, 'chemical', has a long journey from ancient Greek practices of metalworking to the modern science of substances and their reactions. When combined, these morphemes logically describe a technique that uses the principles of immunology (antibody-antigen reactions) to perform chemical analysis on biological tissues, allowing scientists to visually map specific proteins within cells.
Analysis
Structure: immuno (immune) + histo (tissue) + chemical (chemical)
- immuno: From Latin immunis (exempt, free from public service). In modern scientific use, it denotes the immune system or immunity.
- histo: From Greek histos (web, tissue). In modern scientific use, it denotes biological tissue.
- chemical: From Late Latin alchimicus and ultimately Greek khēmeia (art of alloying metals). In modern use, it denotes relating to chemistry or chemicals.
Examples
The diagnosis was confirmed by an immunohistochemical stain that highlighted the tumor markers.
Immunohistochemical analysis is a cornerstone technique in modern pathology laboratories.
Their research relied on immunohistochemical methods to localize the protein expression in the brain tissue.