naltrexone
UK[nalˈtrɛksəʊn]US[nælˈtrɛksoʊn]
n
A synthetic drug that blocks opioid receptors in the brain, used to treat alcohol and opioid dependence.
Morpheme Breakdown
nal
trex
one
nal
sense
trex
sense
one
sense
Etymology
Naltrexone is a modern pharmaceutical name constructed systematically from chemical nomenclature. The name is a portmanteau derived from its chemical relationship to the opioid antagonist naloxone and its structural origin from the opioid oxymorphone. The 'nal-' prefix, shared with naloxone, signals its role as an N-allyl derivative designed to block opioid receptors. The '-trex-' infix is a truncated reference to oxymorphone, and the '-one' suffix is a standard denotation for a ketone functional group in organic chemistry, precisely describing the molecule's structure for scientific and medical professionals.
Analysis
Structure: nal (sense) + trex (sense) + one (sense)
- nal: A contraction from 'N-allyl', indicating the presence of an allyl group attached to a nitrogen atom. This is a chemical nomenclature prefix.
- trex: A contraction from 'oxymorphone', the parent opioid compound from which naltrexone is derived.
- one: A suffix in chemical nomenclature indicating a ketone (a compound containing a carbonyl group).
Examples
The doctor prescribed naltrexone as part of a comprehensive treatment plan for alcohol use disorder.
Naltrexone works by blocking the euphoric and sedative effects of opioids.
Patients must be completely free of opioids before starting naltrexone to avoid severe withdrawal symptoms.