telomerase
telomerase
UK[təˈlɒməreɪz]US[təˈlɑːməreɪs]
n
An enzyme that adds telomeric DNA to the ends of chromosomes, preventing them from shortening during cell division.
Morpheme Breakdown
telomere
ase
telomere
end part,
ase
Etymology
The word 'telomerase' is a modern scientific compound, built from two established components. The first part, 'telomere,' was coined in the 1930s from Greek roots telos (end, completion) and meros (part, portion) to name the protective caps at chromosome ends. The suffix '-ase,' standardized in the late 19th century for naming enzymes, derives from Greek -asis (process or action) via the ending of words like 'diastase.' Thus, 'telomerase' logically denotes the enzyme responsible for acting upon or building the telomere, directly linking its structural composition to its biological function of maintaining chromosomal integrity.
Analysis
Structure: telomere + ase
telomere: From Greek telos (end) + meros (part). A compound noun meaning "end part," referring to the terminal segment of a chromosome.
ase: A suffix of Greek origin via modern scientific Latin, used to form the names of enzymes. It indicates a functional, catalytic molecule.
Examples
Telomerase activity is crucial for the indefinite division of stem cells and certain cancer cells.
Researchers are studying telomerase inhibitors as a potential strategy to combat cancer.
The Nobel Prize was awarded for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase.